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Expert Consensus Document

Periodontitis and Cardiovascular Diseases. Consensus Report

Authors:

M. Sanz ,

Department of Dental Clinical Specialties and ETEP Research Group, Faculty of Odontology, University Complutense of Madrid, Plaza Ramon y Cajal, Madrid, ES
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A. Marco del Castillo,

Cardiology Department, Hospital Universitario Ramon y Cajal, Madrid, ES
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S. Jepsen,

Department of Periodontology, Operative and Preventive Dentistry, University of Bonn, Bonn, DE
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J. R. Gonzalez-Juanatey,

Cardiology Department, University Hospital, University of Santiago de Compostela, IDIS, CIBERCV, ES
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F. D’Aiuto,

Department of Periodontology, Eastman Dental Institute and Hospital, University College London, London, GB
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P Bouchard,

U.F.R. d’odontologie, Université Paris Diderot, Hôpital Rothschild AP-HP, Paris, FR
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I. Chapple,

School of Dentistry, Institute of Clinical Sciences, College of Medical and Dental Sciences, The University of Birmingham, Birmingham, GB
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T. Dietrich,

School of Dentistry, Institute of Clinical Sciences, College of Medical and Dental Sciences, The University of Birmingham, Birmingham, GB
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I. Gotsman,

Heart Institute, Hadassah University Hospital, Jerusalem, IL
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F. Graziani,

Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, IT
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D. Herrera,

Department of Dental Clinical Specialties and ETEP Research Group, Faculty of Odontology, University Complutense of Madrid, Plaza Ramon y Cajal, Madrid, ES
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B. Loos,

ACTA University, Amsterdam, NL
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P. Madianos,

Department of Periodontology, School of Dentistry, National and Kapodistrian University of Athens, GR
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J. B. Michel,

Inserm Unit 1148, laboratory for translational CV science, X. Bichat hospital, Paris, FR
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P. Perel,

World Heart Federation, Geneva, CH; Centre for Global Chronic Conditions, London School of Hygiene and Tropical Medicine, GB
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B. Pieske,

Charité Universitätsmedizin Berlin, Department of Internal Medicine and Cardiology, Berlin, DE; DZHK (German Center for Cardiovascular Research) Partnersite Berlin, German Heart Institut Berlin, DE
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L. Shapira,

Department of Periodontology, Hebrew University – Hadassah Faculty of Dental Medicine, Jerusalem, IL
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M. Schechter,

Leviev Heart Center, Chaim Sheba Medical Center, tel Hashomer and the Sackler Faculty of Medicine, Tel Aviv University, IL
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M. Tonetti,

Department of Periodontology, The University of Hong Kong, Prince Philip Dental Hospital, HK
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C. Vlachopoulos,

Department of Cardiology, National and Kapodistrian University of Athens, GR
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G. Wimmer

Department of Prosthetic Dentistry, School of Dental Medicine, Karl-Franzens University Graz, AT
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Abstract

Background: In Europe cardiovascular disease (CVD) is responsible for 3.9 million deaths (45% of deaths), being ischaemic heart disease, stroke, hypertension (leading to heart failure) the major cause of these CVD related deaths. Periodontitis is also a chronic non‐communicable disease (NCD) with a high prevalence, being severe periodontitis, affecting 11.2% of the world’s population, the sixth most common human disease.

Material and Methods: There is now a significant body of evidence to support independent associations between severe periodontitis and several NCDs, in particular CVD. In 2012 a joint workshop was held between the European Federation of Periodontology (EFP) and the American Academy of Periodontology to review the literature relating periodontitis and systemic diseases, including CVD. In the last five years important new scientific information has emerged providing important emerging evidence to support these associations.

Results and Conclusions: The present review reports the proceedings of the workshop jointly organised by the EFP and the World Heart Federation (WHF), which has updated the existing epidemiological evidence for significant associations between periodontitis and CVD, the mechanistic links and the impact of periodontal therapy on cardiovascular and surrogate outcomes. This review has also focused on the potential risk and complications of periodontal therapy in patients on anti thrombotic therapy and has made recommendations for dentists, physicians and for patients visiting both the dental and medical practices.

How to Cite: Sanz M, del Castillo AM, Jepsen S, Gonzalez-Juanatey JR, D’Aiuto F, Bouchard P, et al.. Periodontitis and Cardiovascular Diseases. Consensus Report. Global Heart. 2020;15(1):1. DOI: http://doi.org/10.5334/gh.400
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Published on 03 Feb 2020.

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