Research Letter
Electrocardiographic Evidence of Cardiac Disease by Sex and HIV Serostatus in Mbarara, Uganda
Authors:
Katherine Kentoffio ,
Center for Global Health, Massachusetts General Hospital, Boston, MA, US
Alfred Albano,
Division of Cardiology, Spectrum Health, Grand Rapids, MI, US
Bruce Koplan,
Division of Cardiovascular Medicine, Brigham and Women’s Hospital, Boston, MA; Harvard Medical School, Boston, MA, US
Maggie Feng,
Center for Global Health, Massachusetts General Hospital, Boston, MA, US
Rahul G. Muthalaly,
Monash Heart, Monash Health, Clayton, Victoria, AU
Jeffrey I. Campbell,
Department of Pediatrics, Boston Medical Center, Boston, MA, US
Ruth Sentongo,
Department of Internal Medicine, Mbarara University of Science and Technology, Mbarara, UG
Russell P. Tracy,
Department of Pathology and Laboratory Medicine, University of Vermont, Burlington, VT, US
Robert Peck,
Center for Global Health at Weill Cornell, Weill Cornell Medical Center for Global Health, New York, NY, US; Department of Internal Medicine, Weill Bugando School of Medicine, Mwanza, TZ
Samson Okello,
Department of Internal Medicine, Mbarara University of Science and Technology, Mbarara, UG
Alexander C. Tsai,
Center for Global Health, Massachusetts General Hospital, Boston, MA; Harvard Medical School, Boston, MA, US
Mark J. Siedner
Center for Global Health, Massachusetts General Hospital, Boston, MA; Harvard Medical School, Boston, MA, US; Department of Internal Medicine, Mbarara University of Science and Technology, Mbarara, UG
Abstract
Highlights
- In this study of middle-aged adults in rural Uganda, we found no difference in the prevalence of abnormal or ischemic electrocardiograms between persons with human immunodeficiency virus (HIV) on stable antiretroviral therapy and HIV-negative comparators.
- Women were more than twice as likely than men to have evidence of myocardial ischemia on electrocardiography, independent of HIV serostatus. This difference persisted after adjustment.
- Additional research is warranted to better evaluate sex-based differences in cardiovascular risk and to further characterize the contributions of HIV cardiovascular disease in this population.
How to Cite:
Kentoffio K, Albano A, Koplan B, Feng M, Muthalaly RG, Campbell JI, et al.. Electrocardiographic Evidence of Cardiac Disease by Sex and HIV Serostatus in Mbarara, Uganda. Global Heart. 2019;14(4):395–7. DOI: http://doi.org/10.1016/j.gheart.2019.08.007
Published on
01 Dec 2019.
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