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Reading: Electrocardiographic Evidence of Cardiac Disease by Sex and HIV Serostatus in Mbarara, Uganda

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Research Letter

Electrocardiographic Evidence of Cardiac Disease by Sex and HIV Serostatus in Mbarara, Uganda

Authors:

Katherine Kentoffio ,

Center for Global Health, Massachusetts General Hospital, Boston, MA, US
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Alfred Albano,

Division of Cardiology, Spectrum Health, Grand Rapids, MI, US
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Bruce Koplan,

Division of Cardiovascular Medicine, Brigham and Women’s Hospital, Boston, MA; Harvard Medical School, Boston, MA, US
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Maggie Feng,

Center for Global Health, Massachusetts General Hospital, Boston, MA, US
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Rahul G. Muthalaly,

Monash Heart, Monash Health, Clayton, Victoria, AU
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Jeffrey I. Campbell,

Department of Pediatrics, Boston Medical Center, Boston, MA, US
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Ruth Sentongo,

Department of Internal Medicine, Mbarara University of Science and Technology, Mbarara, UG
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Russell P. Tracy,

Department of Pathology and Laboratory Medicine, University of Vermont, Burlington, VT, US
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Robert Peck,

Center for Global Health at Weill Cornell, Weill Cornell Medical Center for Global Health, New York, NY, US; Department of Internal Medicine, Weill Bugando School of Medicine, Mwanza, TZ
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Samson Okello,

Department of Internal Medicine, Mbarara University of Science and Technology, Mbarara, UG
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Alexander C. Tsai,

Center for Global Health, Massachusetts General Hospital, Boston, MA; Harvard Medical School, Boston, MA, US
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Mark J. Siedner

Center for Global Health, Massachusetts General Hospital, Boston, MA; Harvard Medical School, Boston, MA, US; Department of Internal Medicine, Mbarara University of Science and Technology, Mbarara, UG
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Abstract

Highlights

  • In this study of middle-aged adults in rural Uganda, we found no difference in the prevalence of abnormal or ischemic electrocardiograms between persons with human immunodeficiency virus (HIV) on stable antiretroviral therapy and HIV-negative comparators.
  • Women were more than twice as likely than men to have evidence of myocardial ischemia on electrocardiography, independent of HIV serostatus. This difference persisted after adjustment.
  • Additional research is warranted to better evaluate sex-based differences in cardiovascular risk and to further characterize the contributions of HIV cardiovascular disease in this population.
How to Cite: Kentoffio K, Albano A, Koplan B, Feng M, Muthalaly RG, Campbell JI, et al.. Electrocardiographic Evidence of Cardiac Disease by Sex and HIV Serostatus in Mbarara, Uganda. Global Heart. 2019;14(4):395–7. DOI: http://doi.org/10.1016/j.gheart.2019.08.007
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Published on 01 Dec 2019.

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