Start Submission Become a Reviewer

Reading: Atrial Fibrillation in Africa—An Under-Reported and Unrecognized Risk Factor for Stroke: A S...

Download

A- A+
Alt. Display

Review

Atrial Fibrillation in Africa—An Under-Reported and Unrecognized Risk Factor for Stroke: A Systematic Review

Authors:

Maartje S. Jacobs ,

Department of Clinical Pharmacy and Toxicology, Martini Hospital, Groningen; University of Groningen, Groningen Research Institute of Pharmacy, Groningen; Department of Health Sciences, University of Groningen, University Medical Center, Groningen, NL
X close

Marinus van Hulst,

Department of Clinical Pharmacy and Toxicology, Martini Hospital, Groningen; Department of Health Sciences, University of Groningen, University Medical Center, Groningen, NL
X close

Abiodun M. Adeoye,

Department of Medicine, College of Medicine, University of Ibadan and University College Hospital, Ibadan; Center for Genomics and Precision Medicine, College of Medicine, University of Ibadan, Ibadan, NG
X close

Robert G. Tieleman,

Department of Cardiology, Martini Hospital, Groningen; Department of Cardiology, University Medical Center, University of Groningen, Groningen, NL
X close

Maarten J. Postma,

University of Groningen, Groningen Research Institute of Pharmacy, Groningen; Department of Health Sciences, University of Groningen, University Medical Center, Groningen; Department of Economics, Econometrics, and Finance, Faculty of Economics and Business, University of Groningen, Groningen, NL
X close

Mayowa O. Owolabi

Department of Medicine, College of Medicine, University of Ibadan and University College Hospital, Ibadan; Center for Genomics and Precision Medicine, College of Medicine, University of Ibadan, Ibadan, NG
X close

Abstract

Over three-quarters of deaths from cardiovascular disease and diabetes occur in low- and middle-income countries, which include many African countries. Global studies showed that the prevalence of the cardiac arrhythmia atrial fibrillation (AF) appeared to be lower in Africa. A systematic search of PubMed and African Journals Online was conducted to determine the prevalence of AF and associated stroke risk factors in Africa and to quantify the need for screening. The publications search yielded a total of 840 articles of which 41 were included. AF was often not identified as the disease of primary interest with its own risks. Data on prevalence in the general population was scarce. The prevalence of stroke risk factors showed a large variation between studies, as well as within clustered subpopulations. AF in Africa is under-reported in published reports. The study types and populations are highly heterogeneous, making it difficult to draw a definitive conclusion on AF prevalence.

Highlights

  • AF is under-reported in published reports from the African region. The focus of published studies seems to be on AF as a risk factor in other comorbid diseases.
  • AF is often not identified as the disease of primary interest with its own risks and complications.
  • More attention needs to be paid to diagnosis and timely detection of AF in Africa. Systematic screening would be a good approach to determine the true prevalence of AF in the general population in Africa.
How to Cite: Jacobs MS, van Hulst M, Adeoye AM, Tieleman RG, Postma MJ, Owolabi MO. Atrial Fibrillation in Africa—An Under-Reported and Unrecognized Risk Factor for Stroke: A Systematic Review. Global Heart. 2019;14(3):269–79. DOI: http://doi.org/10.1016/j.gheart.2019.04.003
5
Views
Published on 01 Sep 2019.
Peer Reviewed

Downloads

  • PDF (EN)

    comments powered by Disqus