Perspectives from NHLBI
Implementation Research: The Fourth Movement of the Unfinished Translation Research Symphony
Authors:
Uchechukwu K. A. Sampson ,
Center for Translation Research and Implementation Science, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, US
David Chambers,
Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, Bethesda, MD, US
William Riley,
Office of Behavioral and Social Sciences Research, National Institutes of Health, Bethesda, MD, US
Roger I. Glass,
Fogarty International Center, National Institutes of Health, Bethesda, MD, US
Michael M. Engelgau,
Center for Translation Research and Implementation Science, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, US
George A. Mensah
Center for Translation Research and Implementation Science, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, US
Abstract
Highlights
- The translational research paradigm has had a dynamic history.
- We propose further evolution of the paradigm to recognize the complex iterative/recursive nature of the translational research process, the feedback loops and intersections that can occur between various steps in the process, as well as the nonlinear progression from fundamental discovery science to population health impact in real-world settings.
- Current evidence shows that the biomedical research enterprise has been highly successful in early translational research while much less success can be demonstrated for late phase translational research, especially T4 translation research.
- The stakes for T4 translation research and implementation science are very high because complete execution of all steps in the translational research spectrum is required for maximum population health impact.
- The welcome news is that there is an ongoing trans-NIH effort that is contributing to a growing symphony of activity within dissemination and implementation research.
How to Cite:
Sampson UKA, Chambers D, Riley W, Glass RI, Engelgau MM, Mensah GA. Implementation Research: The Fourth Movement of the Unfinished Translation Research Symphony. Global Heart. 2016;11(1):153–8. DOI: http://doi.org/10.1016/j.gheart.2016.01.008
Published on
01 Mar 2016.
Peer Reviewed
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