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Assessing the Global Burden of Ischemic Heart Disease: Part 1: Methods for a Systematic Review of the Global Epidemiology of Ischemic Heart Disease in 1990 and 2010

Authors:

Andrew E. Moran ,

Division of General Medicine, Department of Medicine, Columbia University Medical Center, New York, NY, US
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John T. Oliver,

The College of New Jersey Library, The College of New Jersey, Ewing, NJ, US
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Masoud Mirzaie,

Yazd Cardiovascular Research Centre, Shahid Sadoughi University of Medical Sciences, Yazd, IR
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Mohammad H. Forouzanfar,

Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, US
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Marina Chilov,

Augustus C. Long Health Sciences Library, Columbia University, New York, NY, US
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Laurie Anderson,

School of Public Health, University of Washington, Seattle, WA, US
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Janina L. Morrison,

New York City Department of Health and Mental Hygiene, New York, NY, US
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Aayla Khan,

Mailman School of Public Health, Columbia University, New York, NY, US
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Nasen Zhang,

Columbia University College of Physicians and Surgeons, New York, NY, US
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Norrisa Haynes,

Columbia University College of Physicians and Surgeons, New York, NY, US
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Jackie Tran,

School of Population Health, University of Queensland, Brisbane, AU
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Adrianna Murphy,

London School of Hygiene and Tropical Medicine, London, GB
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Vincent DeGennaro,

Division of General Medicine, Department of Medicine, Brigham and Women’s Hospital, Boston, MA, US
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Gregory Roth,

Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA; Division of Cardiology, Department of Medicine, University of Washington, Seattle, WA, US
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Dong Zhao,

Department of Epidemiology, Beijing Institute of Heart, Lung, and Blood Vessel Diseases, Beijing; Capital University of Medical Sciences, Beijing, CN
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Nasheeta Peer,

Chronic Diseases of Lifestyle Research Unit, South African Medical Research Council, Durban, ZA
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Andres Pichon-Riviere,

Institute for Clinical Effectiveness and Health Policy and the University of Buenos Aires, Buenos Aires, AR
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Adolfo Rubinstein,

Institute for Clinical Effectiveness and Health Policy and the University of Buenos Aires, Buenos Aires, AR
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Nana Pogosova,

National Research Center for Preventive Medicine, Moscow, RU
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Dorairaj Prabhakaran,

Centre for Chronic Disease Control and the Public Health Foundation of India, New Delhi, IN
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Mohsen Naghavi,

Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, US
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Majid Ezzati,

MRC-HPA Centre for Environment and Health and Department of Epidemiology and Biostatistics, Imperial College London, London, GB
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George A. Mensah

Department of Medicine, University of Cape Town, Cape Town, ZA
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Abstract

BACKGROUND Ischemic heart disease (IHD) is the leading cause of death worldwide. The GBD (Global Burden of Disease, Injuries, and Risk Factors) study (GBD 2010 Study) conducted a systematic review of IHD epidemiology literature from 1980 to 2008 to inform estimates of the burden on IHD in 21 world regions in 1990 and 2010.

METHODS The disease model of IHD for the GBD 2010 Study included IHD death and 3 sequelae: myocardial infarction, heart failure, and angina pectoris. Medline, EMBASE, and LILACS were searched for IHD epidemiology studies in GBD high-income and low- and middle-income regions published between 1980 and 2008 using a systematic protocol validated by regional IHD experts. Data from included studies were supplemented with unpublished data from selected high-quality surveillance and survey studies. The epidemiologic parameters of interest were incidence, prevalence, case fatality, and mortality.

RESULTS Literature searches yielded 40,205 unique papers, of which 1,801 met initial screening criteria. Upon detailed review of full text papers, 137 published studies were included. Unpublished data were obtained from 24 additional studies. Data were sufficient for high-income regions, but missing or sparse in many low- and middle-income regions, particularly Sub-Saharan Africa.

CONCLUSIONS A systematic review for the GBD 2010 Study provided IHD epidemiology estimates for most world regions, but highlighted the lack of information about IHD in Sub-Saharan Africa and other low-income regions. More complete knowledge of the global burden of IHD will require improved IHD surveillance programs in all world regions.

How to Cite: Moran AE, Oliver JT, Mirzaie M, Forouzanfar MH, Chilov M, Anderson L, et al.. Assessing the Global Burden of Ischemic Heart Disease: Part 1: Methods for a Systematic Review of the Global Epidemiology of Ischemic Heart Disease in 1990 and 2010. Global Heart. 2012;7(4):315–29. DOI: http://doi.org/10.1016/j.gheart.2012.10.004
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Published on 01 Dec 2012.
Peer Reviewed

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