Research
The effects of aerobic exercises on the serum oxidized LDL and total antioxidant capacity in non-active men
Authors:
M.E. Afzalpour,
University of Birjand, Birjand, IR
R. Gharakhanlou,
University of Tarbiat Modares, Tehran, IR
A.A. Gaeini,
University of Tehran, Tehran, IR
H. Mohebbi,
University of Guilan, Guilan, IR
M. Hedayati,
Shaheed Beheshti University of Medical Sciences, Tehran, IR
M. Khazaei
Department of Physiology, Isfahan University of Medical Sciences, Isfahan, IR
Abstract
We investigated the effect of moderate and vigorous aerobic exercise (MAE and VAE) on serum oxidized low-density lipoprotein (ox-LDL) levels and total antioxidant capacity (TAC) in voluntary and untrained healthy subjects. All subjects were randomly divided into three groups, including VAE (80–85% of maximal reserve heart rate) (n = 15), MAE (60–65% of maximal reserve heart rate) (n = 17), and control (n = 12). Exercise groups exercised in three sessions per week for 8 weeks. MAE and VAE did not significantly alter serum ox-LDL, total cholesterol (TC) and TAC (p > 0.05), while serum high-density lipoprotein (HDL-C) and HDL-C/TC ratio were significantly increased (p < 0.05). In the exercise groups, maximal oxygen uptake (VO2max) was higher and body mass index (BMI) was lower than control group (p < 0.05). There was a significant positive correlation between baseline VO2max and TAC and HDL-C. TAC had a significant negative correlation with TC, LDL-C and BMI. We conclude that serum ox-LDL and TAC were not affected by exercise, however, a positive correlation between VO2max and TAC and a negative correlation between TAC and LDL-C as well as TC suggest a correlation between physical training and an improved antioxidant defense system.
How to Cite:
Afzalpour ME, Gharakhanlou R, Gaeini AA, Mohebbi H, Hedayati M, Khazaei M. The effects of aerobic exercises on the serum oxidized LDL and total antioxidant capacity in non-active men. Global Heart. 2008;3(2):77–82. DOI: http://doi.org/10.1016/j.cvdpc.2008.01.002
Published on
01 Apr 2008.
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